Two studies were conducted to examine the use of behavioral cues to identify deception within structured interviews. In Study 1, participants engaged in mock interviews in which they were instructed to lie on specific questions that varied by person. Trained coders evaluated the presence and extent of deception cues in each videotaped response. Nine cues predicted responses as expected, demonstrating that, with careful scrutiny, it is possible to detect deception. In Study 2, participants, either informed or uninformed regarding deception cues, viewed five interviews and evaluated responses as being honest or deceptive. Participants also rated overall interview performance. Participants were unable to accurately distinguish lies from truths. Nevertheless, performance ratings differed on the basis of rater perceptions of truthfulness.